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动脉粥样硬化是一种常见病,多发病。特别是中、老年人,常可引起冠心病、脑血管意外等症,严重地危害着人们的健康和生命。因此防治动脉粥样硬化,探索其机制及寻找有效药物是当今一项重要任务。本研究的目的在于建立家兔实验性动脉粥样硬化模型及观察中药对该模型的治疗效果。材料和方法(简略) 一、动物和分组:雄性纯种健康家兔40只,每只每日喂饲1克胆固醇,持续80天后停药,随机分为模型组、对照组,治疗Ⅰ组、治疗Ⅱ组,每组各10只。每日治疗Ⅰ组喂饲扩冠Ⅰ号12克,治疗Ⅱ组喂饲扩冠Ⅱ号15克,对照组只喂基础饲料。三个月后将动物全部杀死。
Atherosclerosis is a common and frequently-occurring disease. In particular, the elderly and the elderly can often cause coronary heart disease, cerebrovascular accidents and other diseases, and seriously endanger people’s health and life. Therefore, prevention and treatment of atherosclerosis, exploring its mechanism and finding effective drugs are an important task today. The purpose of this study was to establish experimental atherosclerosis model in rabbits and observe the therapeutic effect of traditional Chinese medicine on the model. Materials and Methods (Simplified) 1. Animals and grouping: 40 male purebred healthy rabbits, each fed with 1 g of cholesterol per day, stopping for 80 days, randomly divided into model group, control group, treatment group I, Treatment group II, 10 in each group. The daily treatment group I was fed 12 g of Expanded Crown I. The treatment group II was fed 15 g of Expanded Crown II. The control group was fed only the basal diet. All animals were killed after three months.