SARS-CoV-2 infection aggravates chronic comorbidities of cardiovascular diseases and diabetes in mic

• 作 者: Yuanwu Ma Dan Lu Linlin Bao Ya
• 机 构: KeyLaboratoryofHumanDiseaseComparativeMedicine,BeijingEngineeringResearchCenterforExperimentalAnimal
• 出 处: 动物模型与实验医学(英文)
• 发表日期: 2021年1期
• 关键词: Cardiovascular disease COVID-19 diabetes mellitus mouse model SARS-CoV-2
• 基金项目: National Natural Science Foundation of China,Grant/Award Number:82041008 and 32070543,National Mega Projects of China for Major Infectious Diseases,Grant/Award Number:2017ZX10304402,CAMS Initiative fo

Background:Cardiovascular diseases(CVDs)and diabetes mellitus(DM)are top two chronic comorbidities that increase the severity and mortality of COVID-19.However,how SARS-CoV-2 alters the progression of chronic diseases remain unclear.Methods:We used adenov