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目的:本研究拟通过改良的质量调整生命年来评估外科择期手术患者实施贮存式自身输血(PABD)的临床疗效和实用性,研究制定科学合理的PABD实施方案,有效节约血液资源,为临床贮存式自身输血治疗提供科学指导。方法:选取符合纳入/排除标准并自愿进行PABD的外科择期手术患者200例为研究对象,经过PABD适合度的评估,以评估级别,采用随机法,随机分配成试验组和对照组,每组100例,试验组为PABD组,对照组为异体输血组。用改良的质量调整生命年(IQALY)来分析2组住院时间、不良反应、术后感染及预后情况。评估PABD的临床疗效和实用性,为临床开展贮存式自身输血治疗提供科学可靠有效的依据。结果:在IQALY的分析应用中,我们将较小的值定义为较为优良的生活质量;用IQALY计算得出值:IQALY试验组=16.67;IQALY对照组=34.00。结论:进行PABD的患者,预后情况较好、平均住院天数更少,在手术后输血不良反应和感染少,临床医生在对择期手术患者进行输血治疗时,建议考虑这些后续的效应和作用。
OBJECTIVE: To evaluate the clinical efficacy and practicability of PABD in patients undergoing elective surgical operation through improved quality adjusted life years, and to develop a scientific and rational PABD implementation plan to effectively save blood resources for clinical storage Self-transfusion therapy to provide scientific guidance. Methods: A total of 200 patients undergoing surgical selective surgery with inclusion / exclusion criteria and voluntarily undergoing PABD were selected as study subjects. After assessing the fitness of PABD, the patients were randomly divided into test group and control group For example, the experimental group was PABD group and the control group was allogeneic blood transfusion group. Two groups of length of hospital stay, adverse reactions, postoperative infection, and prognosis were analyzed using the Modified Quality-adjusted Life Year (IQALY). To assess the clinical efficacy and practicability of PABD and provide a scientific and reliable basis for the clinical storage-based self-transfusion therapy. RESULTS: In the IQALY analysis application, we defined a smaller value as a superior quality of life; IQALY calculated values: IQALY trial = 16.67; IQALY control = 34.00. CONCLUSIONS: Patients undergoing PABD have a better prognosis and a lower average length of stay, fewer adverse transfusions and fewer infections after surgery, and it is advisable for clinicians to consider these subsequent effects and effects when transfused in patients undergoing elective surgery.