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洋地黄毒甙过量引起的高钾血症和心律失常是致命的,有效的疗法是增加洋地黄毒甙的排泄。Neur-onen 等曾报告活性炭增加了苯巴比妥的排泄,因为苯巴比妥具有类似洋地黄毒甙的药物动力学特性,因此作者试用重复口服剂量活性炭治疗1例洋地黄过量的患者。1例66岁有高血压和房颤病史的妇女,在服用0.1mg 洋地黄毒甙约100片和0.1mg 利血平6片后4小时被送到急诊室。患者昏睡,血压150/90mmHg,脉搏50/min,虽然心尖搏动向左下移位,但无充血
Digoxigenin overdose caused by hyperkalemia and arrhythmia is fatal, effective therapy is to increase digoxin glycosides excretion. Neuronen et al. Reported that activated carbon increased the excretion of phenobarbital because phenobarbital has pharmacokinetic properties similar to that of digitox and the authors therefore tried repeated orally administered doses of activated charcoal to treat one patient with digitalylan excess. One 66-year-old woman with a history of hypertension and atrial fibrillation was admitted to the emergency room 4 hours after taking about 100 tablets of 0.1 mg digoxigenin and 6 tablets of 0.1 mg reserpine. Patients were drowsy, blood pressure 150 / 90mmHg, pulse 50 / min, although the apical beating shift to the lower left, but no congestion