顺铂、足叶乙苷腹腔化疗联合静脉化疗治疗晚期卵巢上皮癌

• 作 者: 王志民 孙秀华 林荣仙 王瑞斐
• 机 构: 青岛市肿瘤医院妇科!青岛266042,青岛市肿瘤医院妇科!青岛266042,青岛市肿瘤医院妇科!青岛266042,青岛市肿瘤医院妇科!青岛266042
• 出 处: 中国癌症杂志
• 发表日期: 1999年03期
• 关键词: 卵巢上皮癌 腹腔化疗 足叶乙苷 晚期卵巢癌 减瘤术 毒性反应 铂类化疗 无交叉耐药性 药代动力学 次理想

晚期卵巢上皮癌的标准治疗为卵巢肿瘤减瘤术及术后辅助治疗。近年以铂类为基础的化疗使卵巢癌的生存率有了改善，但晚期卵巢癌或术后复发病人预后仍较差。１９９１年１０月～１９９５年６月我院研究用顺铂（ＤＤＰ）、足叶乙苷（Ｖｐ１６）腹腔化疗联合磷酰胺（ＣＴＸ）、顺

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