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纳米羟基磷灰石具有良好的组织相容性,比表面积大,吸附能力强,非常适合作为新型的药物载体,在生物大分子和难溶性药物载体方面有着非常重要的应用。本文选用了热分解的方法完成了Fe_3O_4磁性纳米粒子的制备,以其为核构建了核壳结构的Fe_3O_4@HA磁性纳米微球。借助SEM、XRD、TEM等技术研究了羟基磷灰石及其复合物的组成、结构,并进一步考察了其磁性性能。此羟基磷灰石空心磁性微球在生物医学领域具有较大的应用前景。
Nano-hydroxyapatite has good histocompatibility, large specific surface area and strong adsorption capacity. It is very suitable as a new type of drug carrier and has very important applications in biological macromolecules and insoluble drug carriers. In this paper, the thermal decomposition method was used to prepare the Fe_3O_4 magnetic nanoparticles, and the core-shell Fe_3O_4 @ HA magnetic nanoparticles were successfully synthesized. The composition and structure of hydroxyapatite and its composites were investigated by means of SEM, XRD and TEM. The magnetic properties of the composites were also investigated. This hydroxyapatite hollow magnetic microspheres has great application prospect in the field of biomedicine.