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目的:分析不同剂量孕酮对无排卵型月经失调的临床效果。方法:选取陆丰市人民医院2015年6月至2016年6月的100例无排卵型月经失调患者,按照随机对照原则将患者分为观察组和对照组,其中观察组患者50例采用低剂量孕酮口服方式治疗,对照组患者50例采用高剂量孕酮口服方式治疗。对两组患者的临床治疗效果、撤退性出血情况对比分析。结果:观察组的不良反应症状发生率为2.00%(1/50),1例头晕患者,对照组的不良反应症状发生率为32.00%(16/50),出现了头晕、恶心、头痛、呕吐4种不良反应,分别是5例、3例、4例、4例,两组结果对比,差异具有统计学意义(P<0.05)。结论:采用不同剂量的孕酮口服方式有较好的临床疗效,但是采用低剂量用药方式疗效更优,可以减少不良反应症状出现,改善患者的身体耐受力和出血情况。
Objective: To analyze the clinical effect of different doses of progesterone on anovulatory menstrual disorders. Methods: 100 cases of anovulatory menopausal patients from June 2015 to June 2016 in Lufeng People’s Hospital were selected. According to the randomized control principle, the patients were divided into observation group and control group. 50 cases in observation group were treated with low dose of pregnancy Ketone oral treatment, control group of 50 patients treated with high-dose progesterone oral treatment. The two groups of patients with clinical effects, withdrawal bleeding comparative analysis. Results: The incidence of adverse reactions in the observation group was 2.00% (1/50). In one case of dizziness, the incidence of adverse reactions in the control group was 32.00% (16/50), with dizziness, nausea, headache and vomiting Four kinds of adverse reactions were 5 cases, 3 cases, 4 cases and 4 cases respectively. The difference between the two groups was statistically significant (P <0.05). Conclusion: The oral administration of different doses of progesterone has better clinical curative effect, but the effect of lower dosage is better, which can reduce the symptoms of adverse reactions and improve the patient ’s physical tolerance and bleeding.