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目的了解四川汶川地震后重灾区板房居住人群DM和糖调节受损(IGR)的患病率及伴发特点,探讨其流行特征和相关危险因素。方法采取横断面随机整群抽样的方法 ,在汶川地震发生1年后对重灾区移居板房居住人群3230名进行了筛查,对指尖FBG≥5.0mmol/L或血压≥140/90mmHg者,给予75g OGTT,并行问卷调查、SAS评分及血液生化指标监测。结果确诊DM者326例,患病率为10.09%,标化率4.63%;IGR者200例,患病率6.19%,标化率2.50%;其中新诊断DM为206例,占本次调查63.19%,新诊断IGR为170例,占本次调查85%。地震重灾区居民DM患病率较全国2008年全国DM调查的结果无明显升高,但是其新诊断率增高(63.1%vs.47.6%),IGR者增高(85%vs.69%),新诊断DM(59.7%vs.35.0%)和IGR者(56.5%vs.37%)合并高血压的发生率较其他地区有明显增加,Logistic回归分析表明,年龄、文化程度、家族史、向心性肥胖、BMI、SBP及精神压力与DM发生明显相关。结论汶川地震后重灾区移居板房居民DM与IGR的患病率与我省2008年调查结果无明显差异,但是DM的新诊断率增高,新诊断DM和IGR者合并高血压的发生率较其他地区有明显增加。除了已经被证实的年龄、文化程度、家族史、向心性肥胖、BMI、SBP因素外,严重自然灾害引起的精神压力可能与新诊断DM合并高血压率显著相关。
Objective To understand the prevalence and concomitant features of DM and impaired glucose regulation (IGR) in boarding houses in the disaster-stricken areas after the Wenchuan earthquake in Sichuan Province and to discuss their epidemiological characteristics and related risk factors. Methods A total of 3,230 residents living in bungalow affected by Wenchuan earthquake were screened by random cluster sampling method. One hundred and seventy-three hundred and eighty-three patients with FBG≥5.0mmol / L or blood pressure ≥140 / 90mmHg in fingertip were screened. Give 75g OGTT, parallel questionnaire, SAS score and blood biochemical indicators monitoring. Results There were 326 confirmed DM cases with a prevalence of 10.09% and a standardized rate of 4.63%. There were 200 cases of IGR with a prevalence of 6.19% and a standardization rate of 2.50%. Among them, 206 cases were newly diagnosed DM, accounting for 63.19% of the survey %, Newly diagnosed IGR 170 cases, accounting for 85% of the survey. The prevalence of DM in residents hardest hit by the earthquake was not significantly higher than that of the whole nation in 2008, but the new diagnosis rate was higher (63.1% vs.47.6%) and IGR (85% vs.69%), The incidence of hypertension with diagnosis of DM (59.7% vs.35.0%) and IGR (56.5% vs.37%) was significantly higher than that of other regions. Logistic regression analysis showed that age, education level, family history, central obesity , BMI, SBP and mental stress were significantly correlated with DM. Conclusion The prevalence rates of DM and IGR in the resettled houses in the hardest hit areas after the Wenchuan earthquake were not significantly different from those of our province in 2008, but the new diagnosis rate of DM increased, and the newly diagnosed DM and IGR patients had higher incidence of hypertension There has been a marked increase in the area. In addition to proven age, education, family history, central obesity, BMI, and SBP, stress caused by severe natural disasters may be significantly associated with newly diagnosed DM with hypertension.