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目的为加强抗菌药物临床应用管理,严格控制清洁切口手术预防用药,对腹股沟疝手术预防使用抗菌药物改进前后效果进行分析。方法对2010年6~8月出院的90例腹股沟疝手术患者(改进前)和2011年6~8月出院的92例腹股沟疝手术患者(改进后)抗菌药物预防使用情况进行对比分析。结果 2011年组腹股沟疝手术抗菌药物预防使用率显著低于2010年组(36.96%VS 96.67%,P<0.01);2011年组抗菌药物预防使用疗程合理性及品种选择合理性较2010年组显著提高(P<0.01);2011年组药品总费用及抗菌药物费用显著下降(P<0.01)。两组患者术后手术部位感染率、甲级愈合率差异和住院时间均无统计学意义(P>0.05)。结论腹股沟疝手术预防使用抗菌药物改进后,有利于控制医院抗菌药物使用率,降低患者的经济负担。
Objective To strengthen the clinical application of antimicrobial agents management, strict control of clean incision surgery preventive medication, prevention and treatment of inguinal hernia before and after the use of antimicrobial agents to improve the results were analyzed. Methods Ninety-nine patients with inguinal hernia who were discharged from June to August in 2010 (before improvement) and 92 patients with inguinal hernia after discharge in June to August in 2011 (improved) were compared. Results The prevention and treatment of antibiotics in inguinal hernia in 2011 was significantly lower than that in 2010 (36.96% vs 96.67%, P <0.01). The rational use of antimicrobial agents in 2011 and the rationality of variety selection were more significant than those in 2010 (P <0.01). In 2011, the total cost of drugs and the cost of antimicrobial drugs decreased significantly (P <0.01). There was no significant difference in infection rate, grade A healing rate and length of hospital stay between the two groups (P> 0.05). Conclusion Inguinal inguinal hernia surgery to prevent the use of antimicrobial agents improved, is conducive to the control of hospital antibacterial drug usage, reduce the economic burden on patients.