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目的：探究不同麻醉对老年患者术后认知功能障碍（POCD）产生的影响。方法：将2013年9月期间～2015年7月期间我院收治的94例需行手术的老年患者作为研究对象，依据麻醉方式不同将其划分为参照组（46例）、实验组（48例），分别给予全麻、硬膜麻醉，对比两组的药物用量、PCCD发生率、不同阶段的MMSE评分。结果：实验组的POCD发生率16.67%明显低于参照组39.13%；麻醉前，两组患者MMSE评分对比无显著差异（P＞0.05）。同组内对比，术后6小时、术后12小时、术后36小时评分都比麻醉前评分下降（P＜0.05）。结论：硬膜麻醉应用于老年手术患者，可降低POCD发生率，缩短疾病的恢复时间，具有较高的临床价值。“,”Objective Explore different anesthesia on elderly patients with postoperative cognitive dysfunction (POCD). Methods Will be during September 2013 - July 2015, 94 cases of our hospital during the period of line need surgery in elderly patients as the research object, on the basis of anesthesia different can be divided into control group (46 cases), the experimental group (48 cases), were given general anesthesia and epidural anesthesia, compared two groups the incidence of drug dosage, PCCD, different stage of the MMSE score. Results The experimental group the incidence of POCD 16.67% significantly lower than that of control group 39.13%; Before anesthesia, MMSE score compared two groups of patients had no significant difference (P> 0.05). Within the same group, after 6 hours, 12 hours after operation, postoperative 36 hours score lower than scores before anesthesia (P < 0.05). Conclusions Epidural anesthesia in elderly patients with surgery for, can reduce the incidence of POCD, shorten the recovery time of the disease has high clinical value.