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目的：通过七氟烷与七氟烷加丙泊酚在全身麻醉中维持镇静效果及麻醉苏醒程度的比较，确定单纯七氟烷用于全麻镇静维持的优越性。方法：将120例ASA I-II级的全身麻醉手术患者随机分为单纯七氟烷组（n=60），七氟烷加丙泊酚组（n=60），记录患者术前、术中和术毕MAP、HR、SpO2的变化；术中知晓发生率；术毕苏醒程度以及患者对麻醉效果满意度评分等。结果：术中患者生命体征变化，I组MAP、HR无明显变化，II组MAP、HR波动明显（P＜0.05）；I组、II组术中知晓发生率均为0；术毕苏醒评分4分以上I组明显多于I I组（P＜0.05）；I组满意度评分明显高于I I组（P＜0.05）。结论：与七氟烷加丙泊酚用于全身麻醉维持镇静相比，单纯七氟烷维持镇静具有用药简单，操作方便，可控性强,循环波动小,术毕苏醒完全的优点,大大提高了患者的满意度。“,”Objective To investigate the effects of sevoflurane and sevoflurane plus propofol on maintenance of anesthesia and early recovery of postoperative cognitive function in patients under general anesthesia. Methods One hundred and twenty patients of level ASA I-II were randomized into 2 groups (n= 60): group I was injected intravenously sevoflurane only and group II was given sevoflurane plus propofol. The clinical data were kept regarding mean arterial blood pressure(MAP), heart rate(HR) and arterial oxygen saturation(SPO2) at three different time point(preoperation, intraoperation and postoperation) respectively, as well as intraoperative awareness rates, cognitive status after operation and patient satisfaction scores on anesthetic effect. Results MAP and HR of group II were different at the time of intraoperation compared with preoperation, and postoperation (P< 0. 05). Intraoperative awareness rates are 0 in both groups. The numbers of patients whose postanesthetic recovery scores were over 4 were different in two groups(P< 0.05), and satisfaction scores on anesthetic effect of group I exceeded those of group II(P< 0.05). Conclusion Compared with sevoflurane plus propofol, sevoflurane only in maintenance of anesthesia was simple, easy to operate,easy to control, stable in haemodynamics, better in cognitive status after operation and higher in patient satisfaction scores.