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甲状旁腺激素 (PTH)在动物可引起骨质和骨力增加 ,提示PTH治疗有助人类防治骨折。为了验证这一假说 ,作者对有过椎骨骨折的绝经后妇女进行PTH( 1 3 4)治疗研究。方法 入选研究的妇女均属不卧床病人、绝经至少已 5年且腰脊柱和胸脊柱X线照像至少有 1~ 2处轻至中度?
Parathyroid hormone (PTH) in animals can cause increased bone mass and bone strength, suggesting that PTH treatment helps prevent and treat fractures in humans. To test this hypothesis, the authors conducted a PTH (1 34) treatment study of postmenopausal women with vertebral fractures. Methods The women enrolled in the study were all ambulatory patients with at least 5 years of menopause and at least 1 to 2 mild to moderate radiographs of the lumbar spine and thoracic spine.