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目的:探讨在常规治疗的基础上降纤酶对急性非Q波心肌梗死(NQMI)急诊早期的治疗效果。方法:对发病在12小时内的16例NQMI患者在常规治疗的基础上,使用降纤酶10 u/d连用3天,与10例 NQMI常规治疗比较,监测PT、APTT、FIB、PLT、心肌酶、胸痛缓解、心律失常、梗死后心绞痛。结果:两组治疗前PT、APTT、FIB、PLT无差异,治疗组治疗后PT、APTT、FIB、PLT较治疗前、较对照组治疗后有差异;治疗组酶峰提前,胸痛缓解例数较对照组有差异。结论:降纤酶对NQMI早期急诊治疗安全、有效。
Objective: To investigate the effect of defibrase on the early emergency treatment of acute non-Q wave myocardial infarction (NQMI) on the basis of routine treatment. Methods: Twenty-six patients with NQMI within 12 hours were treated with defibrase 10 u / d for 3 days. Compared with 10 patients treated with NQMI routine therapy, PT, APTT, FIB, PLT, Chest pain relief, arrhythmia, angina after infarction. Results: PT, APTT, FIB and PLT before treatment were not different between the two groups. PT, APTT, FIB and PLT in the treatment group were significantly different from those before the treatment, and were higher in the treatment group than those in the control group Control group differences. Conclusion: Defibrase is safe and effective in the early emergency treatment of NQMI.