【摘 要】
：
Two previously undescribed steroidal compounds,16,23-epoxy-22,26-epimino-cholest-22(N),23,25(26)-trien-3β-ol-3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl-(1 →4)-β-D-galactopyranoside (1) and 26-O-β-D-glucopyranosyl-(25R)-5a-furost-20(22)-en-3β,26-diol
【机 构】
：
School of Chinese Pharmacy, Beijing University of Traditional Chinese Medicine, Beijing 100029, Chin
论文部分内容阅读
Two previously undescribed steroidal compounds,16,23-epoxy-22,26-epimino-cholest-22(N),23,25(26)-trien-3β-ol-3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl-(1 →4)-β-D-galactopyranoside (1) and 26-O-β-D-glucopyranosyl-(25R)-5a-furost-20(22)-en-3β,26-diol (2),together with 7 known ones including 26-O-β-D-glucopyranosyl-(25R)-5,20(22)-dien-furost-3β,26-diol (3),(25R)-5-en-spirost-3β-ol-O-β-D-glucopyranosyl-(1→4)-[a-L-rhmanopyranosyl-(1→2)]-β-D-galactopyranoside (4),funkioside D (5),aspidistrin (6),tigogenin-3-O-β-D-lucotrioside (7),desglucolanatigonin Ⅱ (8),and degalactotigonin (9),were isolated from Solanum lyratum Thunb.Their cytotoxic activities were tested in two cancer cell lines by MTT method.One of the steroidal glycosides (6)showed significant cytotoxic activity against gastric cancer SGC7901 and liver cancer BEL-7402 cells.
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