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本文报道在10例肝癌患者中运用肝静脉暂时闭塞和肝动脉内灌注化疗、栓塞的方法治疗取得较好疗效。7例甲胎蛋白阳性患者5例下降大于50%,2例转阴。4例肿瘤缩小>50%。2例合并肝动-静脉瘘者成功实行碘油栓塞,1例经治疗后肝动-静脉瘘消失。对肝功能的影响与普通介入治疗相同。消化道反应相对较轻。并可提高肿瘤局部药物浓度,延长药物作用时间。配合肝段动脉或靶血管的插管可进一步提高疗效,减少并发症。
This article reports in 10 cases of liver cancer patients with hepatic vein temporary occlusion and intrahepatic infusion chemotherapy, embolization method to achieve better results. Seven cases of alpha-fetoprotein-positive patients decreased by more than 50% in 5 cases, and 2 cases turned negative. In 4 cases, the tumor was reduced by >50%. Two patients with hepatic arteriovenous fistula successfully performed lipiodol embolization, and one case showed disappearance of hepatic arteriovenous fistula after treatment. The effect on liver function is the same as common interventional therapy. Gastrointestinal reaction is relatively light. It can increase the local drug concentration of the tumor and prolong the action time of the drug. Cooperating with the hepatic artery or target vessel can further improve the efficacy and reduce complications.