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目的探讨分析临床治疗中氟喹诺酮类药物的应用状况。方法从2010年7月至2011年6月在我院住院治疗并归档的病例中随机抽取实施抗菌治疗的患者资料1013例,统计分析抗菌治疗中氟喹诺酮类药物的使用状况及作用特点。结果 46%抗菌治疗的患者使用了氟喹诺酮类药物,左氧氟沙星的使用频率最高(占39.48%),联合用药占91.20%,不合理用药占8.80%;52例出现不良反应且多表现为呕吐、恶心、头晕、头痛、静脉炎、皮疹、瘙痒等临床症状。结论临床应用中应注意适应证的掌握及药物剂量、疗程、药物配伍禁忌等,避免不良反应的发生
Objective To investigate the clinical application of fluoroquinolones. Methods From July 2010 to June 2011, 1013 cases of patients receiving antibacterial therapy were randomly selected from the hospitalized and archived cases in our hospital, and the statistical analysis of the use status and the characteristics of fluoroquinolones in the antibacterial treatment were statistically analyzed. Results 46% of patients treated with antibacterials used fluoroquinolones, levofloxacin had the highest frequency of use (39.48%), combination therapy accounted for 91.20% and unreasonable use of drugs accounted for 8.80%; 52 patients showed adverse reactions and showed more vomiting, nausea , Dizziness, headache, phlebitis, rash, itching and other clinical symptoms. Conclusion Clinical application should pay attention to the master of indications and drug dose, treatment, drug compatibility Taboo, to avoid the occurrence of adverse reactions