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用荧光光谱滴定法测定了单-[6-(二乙烯三胺)-6-脱氧]-β-环糊精(1)、单-[6-(三乙烯四胺)-6-脱氧]-β-环糊精(2)及其铜配合物(3,4)与一系列萘衍生物在磷酸缓冲溶液(pH7.2,0.lmol·dm~(-3)中,25℃时形成超分子体系的稳定常数,并与母体β-环糊精的配位能力进行了比较.化学计量法表明,四种化学修饰β-环糊精与萘衍生物形成了1:1的超分子配合物.从尺寸适合、几何互补及多点识别等方面讨论了主体化合物对模型底物的分子选择性键合能力.结果表明,疏水相互作用、范德华力、静电相互作用及氢键等多种非共价键弱相互作用协同贡献于超分子配合物的形成,主-客体间的结构匹配在分子受体选择性键合底物形成超分子配合物中起重要作用.
The fluorescence spectra of mono- [6- (diethylenetriamine) -6-deoxy] -β-cyclodextrin (1) and mono- [6- (triethylenetetramine) -6-deoxy] β-cyclodextrin (2) and its copper complexes (3,4) with a series of naphthalene derivatives in phosphate buffer solution (pH7.2,0.lmol · dm ~ (-3), formed at 25 ℃ super The stability constant of the molecular system was compared with that of the parent β-cyclodextrin.The stoichiometry showed that four kinds of chemically modified β-cyclodextrin and naphthalene derivatives formed a 1: 1 supramolecular complex The molecular selective bonding of host compounds to model substrates was discussed from the aspects of size, geometric complementarity and multi-point recognition.The results showed that hydrophobic interactions, van der Waals forces, electrostatic interactions and hydrogen bonding The weak interaction of valence bonds contributes to the formation of supramolecular complexes, and the structural matching between host and guest plays an important role in the formation of supramolecular complexes by selective bonding of substrates by molecular receptors.