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氯氮平村氧化物（刀）是氯氮乎（I）的主要代谢物，对精神病人研究中发现，血浆中总（I）浓度有10％～25％为（刀），本文报道了碱化血浆的提取分析方法和在GLC－MS测定中（刀）的热不稳定性。HPLC条件HPLC系统：氰基柱4．6mhX150mm，3pm；流动相为gO％乙睛和10％0．08mol·L‘
Clozapine oxide (knife) is the main metabolite of chlorine nitrogen (I), the study of psychiatric patients found that the total plasma concentration (I) 10% ~ 25% for the (knife) Methods for the extraction and analysis of plasmatized plasma and thermal instability in the GLC-MS assay (knife). HPLC conditions HPLC system: Cyano column 4.6mhX150mm, 3pm; mobile phase gO% acetonitrile and 10% 0.08mol · L ’