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目的探讨研究4%白蛋白生理盐水+羟乙基淀粉替代部份血浆在血液病血浆置换治疗中应用效果。方法选取2015年1月至2016年11月来我院就诊治疗的78例血液病患者作为实验对象,采用随机法分成观察组与对照组,观察组40例,对照组38例,观察组采用4%白蛋白生理盐水+羟乙基淀粉替代部分血浆治疗法,对照组采用传统血浆置换治疗法,比较分析两组患者血浆置换术前后相关检验指标及临床症状。结果观察组患者术后血红蛋白、血小板上升、网织红细胞下降,血肌酐及尿素氮等达到正常水平,凝血功能不受影响,临床症状、体征明显改善或消失,不良反应及其他并发症少见,与全血浆置换相比疗效相当。结论 4%白蛋白生理盐水+羟乙基淀粉替代部份血浆在血液病血浆置换治疗中具有较好的效果,能有效缓解血源紧缺状况,减少患者住院时间及经济负担,并能有效降低患者死亡风险,值得使用与推广。
Objective To investigate the application of 4% albumin normal saline and hydroxyethyl starch instead of part of plasma in the treatment of hematological diseases. Methods From January 2015 to November 2016, 78 cases of hematological diseases treated in our hospital were selected as the experimental subjects. The patients in the observation group and the control group were randomly divided into observation group (40 cases) and control group (38 cases), and observation group % Albumin normal saline + hydroxyethyl starch instead of part of the plasma treatment, the control group using traditional plasmapheresis therapy, comparative analysis of the two groups of patients before and after plasma exchange related test indicators and clinical symptoms. Results In the observation group, the postoperative hemoglobin, thrombocytopenia, reticulocyte decline, serum creatinine and urea nitrogen reached the normal level, the coagulation function was not affected, clinical symptoms and signs improved or disappeared obviously, and adverse reactions and other complications were rare. Full plasma exchange comparable efficacy. Conclusion The replacement of some plasma with 4% albumin normal saline and hydroxyethyl starch has a good effect in plasma exchange of hematological diseases, which can effectively relieve the shortage of blood supply, reduce the hospitalization time and economic burden, and effectively reduce the patients’ The risk of death is worth using and promoting.