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目的研究急性冠状动脉综合征(ACS)患者的总胆固醇(TC)、超敏C反应蛋白(hs-CRP)水平与经皮冠状动脉介入治疗(PCI)术无复流现象的相关性。方法选择30例行PCI术出现无复流现象的急性冠状动脉综合征患者为A组,随机选取同期行PCI术未出现无复流现象的急性冠状动脉综合征患者40例为B组,比较两组患者总胆固醇、低密度脂蛋白胆固醇、超敏C反应蛋白水平。结果 A组患者超敏C反应蛋白为(8.45±0.34)mg/L、总胆固醇为(7.69±0.41)mmol/L、低密度脂蛋白胆固醇为(5.63±0.53)mmol/L,均高于B组的(5.26±0.31)mg/L、(6.21±0.45)mmol/L、(4.10±0.51)mmol/L,差异具有统计学意义(P<0.05)。结论总胆固醇、超敏C反应蛋白水平与PCI术出现无复流现象有明显相关性。
Objective To investigate the relationship between total cholesterol (TC), high-sensitivity C-reactive protein (hs-CRP) levels and no-reflow phenomenon in patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention. Methods A total of 30 patients with acute coronary syndrome who had no-reflow phenomenon under PCI were selected as group A. 40 patients with acute coronary syndrome who did not show no-reflow at the same period were randomly selected as group B, Group of patients with total cholesterol, low density lipoprotein cholesterol, high-sensitivity C-reactive protein levels. Results In group A, the high-sensitivity C-reactive protein was (8.45 ± 0.34) mg / L, total cholesterol was (7.69 ± 0.41) mmol / L and low density lipoprotein cholesterol was (5.63 ± 0.53) (5.26 ± 0.31) mg / L, (6.21 ± 0.45) mmol / L and (4.10 ± 0.51) mmol / L respectively. The difference was statistically significant (P <0.05). Conclusion There is a significant correlation between total cholesterol and high-sensitivity C-reactive protein and no-reflow phenomenon in PCI.