论文部分内容阅读
目的分析奥曲肽联合中心静脉导管腹腔引流治疗肝硬化顽固性腹水的疗效。方法选取我院2012年4月—2016年4月收治的肝硬化顽固性腹水患者63例,随机分为对照组(n=30)和观察组(n=33)。对照组采用中心静脉导管腹腔引流治疗,观察组采用奥曲肽联合中心静脉导管腹腔引流治疗,对比2组治疗效果。结果观察组患者治疗的总有效率为84.85%,对照组患者治疗的总有效率为53.33%,差异具有统计学意义(P<0.05);2组患者不良反应发生率比较差异无统计学意义(P>0.05)。结论奥曲肽联合中心静脉导管腹腔引流治疗肝硬化顽固性腹水可有效提升循环血容量,降低门静脉压力,缓解患者的临床症状,疗效显著,具有较高的实用价值。
Objective To analyze the curative effect of intraperitoneal drainage of octreotide combined with central venous catheter in treatment of refractory cirrhosis and ascites. Methods Sixty-three patients with cirrhosis and refractory ascites admitted from April 2012 to April 2016 in our hospital were randomly divided into control group (n = 30) and observation group (n = 33). The control group was treated with central venous catheter drainage, the observation group was treated with octreotide plus central venous catheter for peritoneal drainage, and the therapeutic effect was compared between the two groups. Results The total effective rate was 84.85% in the observation group and 53.33% in the control group (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups P> 0.05). Conclusion Intraperitoneal drainage of octreotide combined with central venous catheter in the treatment of refractory ascites caused by cirrhosis of the liver can effectively improve the blood volume of circulation, reduce the pressure of portal vein and relieve the clinical symptoms of patients. The therapeutic effect is significant and has high practical value.