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目的 探讨影响女性 2型糖尿病合并无症状菌尿 (ASB)的主要危险因素以及有关临床特点。方法 采用病例对照研究 ,2型糖尿病伴无症状菌尿 (ASB+ )组 12 8例 ,2型糖尿病不伴ASB(ASB-)组 30 0例 ,正常对照组 74例。结果 ①女性 2型糖尿病合并ASB的发病率为 30 % ;②与ASB有关的危险因素包括年龄、病程、糖尿病视网膜病变、糖尿病肾病、糖尿病神经病变、既往尿路感染史、大血管疾病、高脂血症、绝经史 ,其中最主要的 3个危险因素是年龄、大量白蛋白尿、既往尿路感染史 ;③随着糖尿病肾病、视网膜病变病情的加重 ,糖尿病合并ASB的发病率也相应增加 ;④糖尿病合并ASB+ 中段尿培养病原微生物以大肠埃希菌为主。结论 ①影响女性 2型糖尿病合并ASB的因素众多 ,主要因素是年龄、大量白蛋白尿、既往尿路感染史 ;②血糖对女性 2型糖尿病合并ASB发病作用降低 ;③ASB可能是女性 2型糖尿病的一个并发症。
Objective To investigate the main risk factors and clinical features of female type 2 diabetes mellitus with asymptomatic bacteriuria (ASB). Methods A case-control study was performed in 128 patients with type 2 diabetes mellitus with asymptomatic bacteriuria (ASB +), 300 with type 2 diabetes without ASB (ASB) and 74 with normal controls. Results ① The incidence of type 2 diabetes in women with ASB was 30%. ② The risk factors associated with ASB included age, duration of diabetic retinopathy, diabetic nephropathy, diabetic neuropathy, previous history of urinary tract infection, macrovascular disease, The main risk factors are age, massive albuminuria and previous history of urinary tract infection. With the exacerbation of diabetic nephropathy and retinopathy, the incidence of ASB in diabetes mellitus also increases accordingly. ④ diabetes with ASB + urine culture pathogenic microorganisms to Escherichia coli-based. Conclusions ① There are many factors that affect ASB in women with type 2 diabetes. The main factors are age, massive albuminuria and previous history of urinary tract infection. ② The incidence of ASB is reduced in women with type 2 diabetes mellitus; ③ ASB may be female type 2 diabetes mellitus A complication