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目的进行双能CT电子密度图像的重建和数值校准,以获得精确的电子密度图像。方法首先基于医学双能CT(DECT)基物质分解成像的基本原理,计算得到理论上的电子密度图像,以及高、低两种不同能量水平下的、关于X射线线性衰减系数的单能图像;然后将两种不同能量水平下的X射线线性衰减系数之组合与电子密度理论值进行线性拟合(Δμ-ρ_e)并计算拟合优度;最后由最佳拟合优度实现医学DECT电子密度图像的重建和校准。结果仿真实验及定量分析结果表明,本文方法得到的电子密度重建图像像素值更加准确,图像质量更高;实际数据实验表明了本文方法的有效性。结论本文实现了一种实用、准确的医学DECT电子密度图像重建和数值校准方法。
Objective To reconstruct and calibrate dual-density CT electron density images to obtain accurate electron density images. Methods Based on the basic principle of medical dual-energy CT (DECT) decomposition, the theoretical electron density images and single-energy images about the linear attenuation coefficients of X-ray at high and low energy levels were calculated. Then, the linear fit (Δμ-ρ_e) of the linear attenuation coefficient of X-ray under two different energy levels and the electron density theoretical value was calculated and the goodness of fit was calculated. Finally, the best DECT electron density Image reconstruction and calibration. Results The results of simulation and quantitative analysis show that the pixel density of electron density reconstruction image obtained by this method is more accurate and the image quality is higher. The experimental results show the effectiveness of the proposed method. Conclusion This paper presents a practical and accurate medical DECT electron density image reconstruction and numerical calibration method.