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洛美沙星是二氟喹诺酮类口服广谱抗菌药.对50万株多种病原菌的测定显示,奈瑟氏球菌属、肠杆菌科的大多数菌属(沙门氏菌属、产毒素志贺氏菌等)、军团菌对其高度敏感;假单胞菌属(包括铜绿假单胞菌)和不动杆菌属对其中度敏感;洛美沙星对衣原体、枝原体、结核分枝杆菌等也具有活性,但弱于对革兰氏阴性菌和阳性菌的活性.临床应用洛美沙星治疗呼吸道、泌尿生殖道、消化道、皮肤、软组织和骨组织感染,烧伤和风湿性疾病感染,以及作为联用抗菌药之一治疗结核病均有显著或良好疗效.洛美沙星的毒性低,光毒性反应的发生率稍高(2.4%),患者对剂量<800mg/d、疗程<4周的耐受性良好.
Lomefloxacin is a fluoroquinolone oral broad-spectrum antibacterial agent.According to the survey of 500,000 strains of many pathogens, Neisseria, Enterobacteriaceae most genus (Salmonella, Shigella toxin ), Legionella is highly susceptible to it; Pseudomonas (including Pseudomonas aeruginosa) and Acinetobacter are moderately sensitive to it; Lomefloxacin is also active against Chlamydia, Mycoplasma, M. tuberculosis and the like , But weaker than those against Gram-negative bacteria and positive bacteria Clinical application of Lomefloxacin for the treatment of respiratory tract, genitourinary tract, digestive tract, skin, soft tissue and bone tissue infections, burns and rheumatic infections, One of the antimicrobial agents for treatment of tuberculosis has a significant or good effect.Lomesofloxacin low toxicity, the incidence of phototoxic reactions slightly higher (2.4%), the patient dose <800mg / d, <4 weeks of treatment is good .