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目的探讨2型糖尿病患者糖化血红蛋白水平与血糖、血脂之间的关系。方法对糖尿病组及正常对照组同时测定糖化血红蛋白(HbAlc)、空腹血糖(FBG)、甘油三脂(TG)、总胆固醇(CH)、高密度脂蛋白(HDL-C)及低密度脂蛋白(LDL-C),对两组的检测结果进行比较,分析糖化血红蛋白与空腹血糖及各项检测是否具有相关性。结果2型糖尿病组的HbAlc、FBG、TG、CH及LDL-C明显高于健康对照组,HDL-C则低于健康对照组,差异有显著性(P<0.05)。糖尿病组HbAlc与FBG,TG,CH,LDL-C各项结果的关系不明显。结论2型糖尿病患者血脂几率显著高于正常人,其血中HbAlc与FBG、TG存在正相关关系,与TC,HDL-C、LDL-C关系不明显。糖化血红蛋白与血糖、血脂同时检测在糖尿病的预防和治疗过程中有一定的参考价值。
Objective To investigate the relationship between the level of glycosylated hemoglobin (HbA1c) and blood glucose and blood lipid in type 2 diabetic patients. Methods The serum levels of HbAlc, FBG, TG, CH, HDL-C and LDL-C in diabetic patients and normal controls were measured. LDL-C), the two groups of test results were compared, analysis of glycosylated hemoglobin and fasting blood glucose and the test is relevant. Results The levels of HbAlc, FBG, TG, CH and LDL-C in type 2 diabetes mellitus were significantly higher than those in healthy controls and HDL-C was significantly lower than that in healthy controls (P <0.05). The relationship between HbAlc and FBG, TG, CH and LDL-C in diabetic patients was not obvious. Conclusion Serum lipids in patients with type 2 diabetes mellitus are significantly higher than those in normal people. There is a positive correlation between HbA1c and FBG, TG in blood and no significant relationship with TC, HDL-C and LDL-C. Glycosylated hemoglobin and blood glucose, lipid testing at the same time in the prevention and treatment of diabetes have a certain reference value.