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目的研究脑心通联合阿司匹林治疗老年缺血性脑血管病的临床效果。方法将2013年5月至2015年10月100例老年缺血性脑血管病患者随机分为对照组50例,行降压、降脂、降糖等常规治疗,并加用阿司匹林进行治疗;研究组50例,在对照组治疗基础上再服用脑心通胶囊进行联合治疗。比较两组患者治疗前后血脂水平、血流动力学指标、血压水平变化。结果治疗后两组患者总胆固醇(TCHO)、三酰甘油(TG)、低密度脂蛋白(LDL)、收缩压、舒张压水平均有所降低,但对照组患者下降程度差于研究组,差异有统计学意义(P<0.05);且治疗后对照组患者血流动力学各项指标与治疗前比较差异未见统计学意义(P>0.05),治疗后研究组血流动力学各项指标明显低于治疗前,且低于对照组,差异有统计学意义(P<0.05)。结论采用阿司匹林联合脑心通治疗老年缺血性脑血管病效果显著,能有效调节机体内血黏度、血压、血脂水平,减轻临床症状,提高患者生活质量。
Objective To study the clinical effect of Naoxintong combined with aspirin in the treatment of senile ischemic cerebrovascular disease. Methods From May 2013 to October 2015, 100 elderly patients with ischemic cerebrovascular disease were randomly divided into control group (n = 50) and received conventional therapy such as hypotensive, hypolipidemic and hypoglycemic agents plus aspirin Group of 50 cases, in the control group based on the treatment and then take Naoxintong capsules for joint treatment. Blood lipid levels, hemodynamic parameters and blood pressure levels before and after treatment were compared between the two groups. Results After treatment, the levels of total cholesterol (TCHO), triglyceride (TG), low density lipoprotein (LDL), systolic blood pressure and diastolic blood pressure decreased in both groups, but the decline in the control group was worse than that in the study group (P <0.05). After treatment, the indexes of hemodynamics in the control group were not significantly different from those before treatment (P> 0.05). After treatment, all indexes of hemodynamics Significantly lower than before treatment, and lower than the control group, the difference was statistically significant (P <0.05). Conclusion The combination of aspirin and Naoxintong is effective in treating elderly patients with ischemic cerebrovascular disease, which can effectively regulate the blood viscosity, blood pressure and blood lipid, alleviate the clinical symptoms and improve the quality of life of patients.