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目的:观察青霉素治疗胎传先天梅毒的临床疗效。方法:2004年1月—2013年12月,治疗胎传先天梅毒共计26例,采用水剂青霉素钠盐(5~10)μg/(kg·d)肌注,连用15天。结果:26例患儿经过治疗血清梅毒螺旋抗原试验(TPPA)25例全部阴转,1例(12岁女童)晚期先天梅毒未转阴。非梅毒螺旋体抗原试验(RPR)26例全部转阴。结论:胎传先天性梅毒采用水剂青霉素治疗疗效快,安全,治愈率高,值得首选推广应用。
Objective: To observe the clinical efficacy of penicillin in the treatment of congenital syphilis with fetal transmission. Methods: From January 2004 to December 2013, a total of 26 cases of congenital syphilis were treated with penicillin sodium (5 ~ 10) μg / (kg · d) intramuscularly for 15 days. Results: Twenty-six children underwent TPV (25 cases), while one case (12-year-old girl) had no congenital syphilis. Non-Treponema pallidum antigen test (RPR) 26 cases were all negative. Conclusion: Congenital syphilis of fetal use of water penicillin treatment of quick, safe, high cure rate, it is preferred to promote the use of.