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DNA聚合酶β有修复被化疗药物破坏的DNA的作用。作者以生物活性为导向从红光树属植物K.elegans Warb.中分得2个强DNA聚合酶β抑制成分(+)-myristinin A和D(1和2),这2个化合物还具有使Cu2+依赖的DNA链断裂的作用。该植物树干木质部依次用己烷、丁酮、甲醇和水提取,将显示DNA聚合
DNA polymerase beta has the effect of repairing DNA destroyed by chemotherapeutic drugs. The authors directed two strong DNA polymerase beta inhibitors (+)-myristinin A and D (1 and 2) from the genus K.elegans Warb. The role of Cu2+-dependent DNA strand breaks. The xylem of the trunk of the plant is extracted with hexane, butanone, methanol and water in order and will show DNA polymerization.