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为了解浙江省吸毒人员HIV、HBV、HCV感染情况,收集浙江省戒毒人员血浆182份,其中静脉吸毒者(IVDUs)64份,非静脉吸毒者(NIVDUs)118份。用ELISA法检测抗HIV,用EIA法检测HBV标志物和抗HCV。结果发现,浙江省吸毒戒毒人员抗HIV阳性率为0%,IVDUs组HBV总感染率为67.18%(43/64),HBsAg携带率为10.93%(7/64),HBeAg阳性7.81%(5/64),抗HCV阳性21.88%(14/64);NIVDUs组HBV总感染率为71.19%(84/118),HBsAg携带率为15.25%(18/118),HBeAg携带率为15.25%(18/118),HBeAg阳性5.93%(7/118),抗HCV阳性0.84%(1/18)。HBV标志物阳性率IVDUs和NIVDUs间无显著性差异(P>0.05),抗HCV阳性率两组间有非常显著性差异(P<0.001)。结果提示,浙江省为HIV感染低发区,为HBV感染高流行区,静脉吸毒为HCV感染的高危因素
In order to understand HIV, HBV and HCV infection among drug addicts in Zhejiang Province, 182 plasma samples were collected from 64 drug addicts in Zhejiang Province, including 64 intravenous drug users (IVDUs) and 118 non-intravenous drug users (NIVDUs). Anti-HIV was detected by ELISA, HBV markers and anti-HCV were detected by EIA. The results showed that the positive rate of HIV in drug addicts was 0% in Zhejiang province, 67.18% (43/64) in IVDUs, 10.93% (7/64) in HBsAg and 7 . The positive rate of anti-HCV was 21.88% (14/64) in NIVDUs group, 71.19% (84/118) in NIVDUs group and 15.25% 118), HBeAg carrier rate was 15.25% (18/118), HBeAg positive was 5.93% (7/118) and anti-HCV was 0.84% (1/18). The positive rate of HBV markers between IVDUs and NIVDUs was not significantly different (P> 0.05). There was a significant difference between the two groups (P <0.001). The results suggest that Zhejiang Province is a low incidence of HIV infection for the high prevalence of HBV infection, intravenous drug use as a risk factor for HCV infection