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目的观察泮托拉唑的疗效及安全性。方法将经内镜确诊的消化性溃疡患者60例随机分成两组,治疗组(A组)30例,静脉滴注泮托拉唑钠40mg,对照组(B组)30例,静脉滴注奥美拉唑钠40mg,均为2次/d,疗程3～5d,之后两药均改口服,20mg/次,1次/d,疗程4周。结果治疗组与对照组的愈合率分别为75.9%和75.0%,总有效率分别为96.7%和93.3%,组间比较无显著性差异(P>0.05);两组不良反应均极轻。结论泮托拉唑治疗消化性溃疡疗效很满意。
Objective To observe the efficacy and safety of pantoprazole. Methods 60 patients with peptic ulcer diagnosed by endoscopy were randomly divided into two groups. The treatment group (group A) 30 cases, the intravenous infusion of pantoprazole sodium 40 mg, the control group (group B) 30 cases, intravenous drip Melazepam sodium 40mg, are 2 times / d, course of treatment 3 ~ 5d, after two drugs were changed oral, 20mg / time, 1 / d, treatment for 4 weeks. Results The healing rates of the treatment group and the control group were 75.9% and 75.0%, respectively. The total effective rates were 96.7% and 93.3% respectively. There was no significant difference between the two groups (P> 0.05). The adverse reactions in both groups were extremely mild. Conclusions Pantoprazole is very satisfactory in the treatment of peptic ulcer.