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透明质酸(HA)是反映肝内皮细胞功能和肝硬化的有实用价值的新指标,也是肝癌诊断的一项补充指标,在国内的研究刚刚起步。唾液酸(SA)为恶性肿瘤的诊断指标之一,但缺乏特异性。联合测定HA.SA对原发性肝癌的诊断价值尚少见报告。我们观察了肝硬化27例,原发性肝癌28例,其它恶性肿瘤17例的血清HA.SA的变化,探讨其对原发性肝癌的诊断价值。
Hyaluronic acid (HA) is a new index that reflects the function of liver endothelial cells and liver cirrhosis. It is also a supplementary indicator for the diagnosis of liver cancer. The research in China has just started. Sialic acid (SA) is one of the diagnostic indicators of malignant tumors, but the lack of specificity. Joint determination of HA.SA diagnostic value of primary liver cancer is still rare. We observed the changes of serum HA.SA in 27 cases of cirrhosis, 28 cases of primary hepatocellular carcinoma and 17 cases of other malignant tumors, and discussed its diagnostic value in primary liver cancer.