论文部分内容阅读
正在积累的证据表明,轻度高草酸尿与“原因不明”的草酸钙肾结石有关。例如活跃结石病人的尿草酸含量明显高于正常人或不活跃结石病人。尿草酸浓度增加较尿钙浓度增加对改变尿草酸饱和度的影响大,约大15倍。所以降低尿草酸含量被设想是防止新结石形成的最有效方法。因此需要复习草酸盐的肠道吸收,体内合成及其排出的研究。
Accumulating evidence suggests that mild hyperoxaluria is associated with calcium oxalate kidney stones of “unexplained” origin. For example, patients with active stone urinary oxalate acid content was significantly higher than normal or inactive stone patients. The effect of increasing urinary oxalic acid concentration on urinary oxalic acid saturation is greater than that of increasing urinary calcium concentration, about 15 times greater. So reducing urinary oxalate content is envisioned as the most effective way to prevent the formation of new stones. Therefore, we need to review the oxalate intestinal absorption, in vivo synthesis and discharge studies.