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目的:探讨和总结睾丸间质细胞瘤的临床表现、诊断与治疗。方法:回顾性分析2例睾丸间质细胞瘤患者的临床资料:2例均为青春期后发病,分别因隐睾肿痛伴发热及不育超声检查发现睾丸肿物入院。B超均为界限清楚的实性低回声结节,大小分别为2.1cm×1.5cm和1.0cm×0.8cm,瘤标及激素水平均正常。结果:2例均行根治性睾丸切除术,术中快速冷冻切片病理检查诊断为睾丸间质细胞瘤。术后病理表现为瘤细胞呈弥漫片状排列,多角形,胞质丰富嗜酸性。分别随访32和2个月,未见复发和转移。结论:睾丸间质细胞瘤临床罕见,确诊依赖病理组织学检查,术前细针穿刺活检有助于选择手术方式,尤其是青春期前的患者。
Objective: To investigate and summarize the clinical manifestations, diagnosis and treatment of testicular leukemia. Methods: The clinical data of 2 cases of testicular stromal tumor were retrospectively analyzed. Two cases were post-puberty onset. Testis masses were admitted to the hospital due to cryptorchidism and pain, fever and infertility respectively. B-ultrasound are clearly defined solid hypoechoic nodules, the size of 2.1cm × 1.5cm and 1.0cm × 0.8cm, tumor markers and hormone levels were normal. Results: Radical orchidectomy was performed in both of the 2 cases, and rapid frozen section biopsy was diagnosed as testicular stromal tumor. Postoperative pathological manifestations of tumor cells were diffuse patchy arrangement, polygonal, cytoplasm rich acidophilic. Follow-up 32 and 2 months, no recurrence and metastasis. Conclusion: Testicular stromal tumor is rare in clinic. The diagnosis depends on histopathological examination. Preoperative fine needle aspiration biopsy is helpful to choose surgical method, especially pre-puberty patients.