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树突状细胞(DC)是目前功能最强的抗原提呈细胞,在机体抗肿瘤免疫中发挥重要作用。近年来,DC瘤苗抗肿瘤临床应用取得较大进展,现对DC瘤苗的制备及其在肿瘤免疫治疗中的临床应用以及存在问题作一综述。
Dendritic cells (DCs) are currently the most potent antigen presenting cells and play an important role in the anti-tumor immunity of the body. In recent years, DC tumor vaccine has made great progress in anti-tumor clinical application, and now the preparation of DC tumor vaccine and its clinical application in tumor immunotherapy and the existing problems are reviewed.