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目的:分析浙江武义地区孕妇发生早期自然流产的现状及影响因素,为预防自然流产提供依据。方法:选取2015年1-12月期间在武义地区医院妇产科诊断为早期自然流产的孕妇690例,将其作为观察组,另选取同期在医院足月正常分娩的孕妇690例,将其作为对照组。对两组孕妇的一般资料、环境、生活习惯及心理情况进行调查并比较,对影响发生早期自然流产的危险因素进行分析。结果:观察组690例早期自然流产孕妇中210例出现不良妊娠结局,占30.4%。经多因素Logistic回归分析,结果显示,影响孕妇发生早期自然流产的独立危险因素主要包括高龄、既往流产史、被动吸烟、生活场所装修异味持续时间长、每天手机使用次数较多、焦虑情绪、合并全身性疾病、内分泌异常及免疫功能异常等,具有统计学意义(P<0.05)。结论:浙江武义地区早期自然流产孕妇不良妊娠结局发生率相对较高,临床医师应针对危险因素对妊娠早期妇女进行孕期指导。
Objective: To analyze the current situation and influencing factors of early spontaneous abortion in pregnant women in Wuyi, Zhejiang Province, and provide evidence for prevention of spontaneous abortion. Methods: 690 pregnant women diagnosed as early spontaneous abortion in obstetrics and gynecology department of Wuyi district from January to December in 2015 were selected as the observation group, and 690 pregnant women of normal term delivery during the same period in the hospital were selected as Control group. The general information, environment, living habits and psychological conditions of two groups of pregnant women were surveyed and compared, and the risk factors affecting early spontaneous abortion were analyzed. Results: In the observation group of 690 cases of early spontaneous abortion, 210 cases of adverse pregnancy outcomes, accounting for 30.4%. Multivariate Logistic regression analysis showed that the independent risk factors affecting early spontaneous abortion in pregnant women mainly include the history of old age, previous abortion, passive smoking, long-term odor of living decoration, daily use of mobile phones, anxiety, mergers Systemic disease, endocrine abnormalities and immune dysfunction, with statistical significance (P <0.05). Conclusion: The incidence of adverse pregnancy outcomes in early spontaneous abortion in Wuyi district of Zhejiang Province is relatively high. Clinicians should provide guidance for pregnant women in early pregnancy for risk factors.