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本文以胃镜检查确诊的胃、十二指肠溃疡患者为实验组,检测其血浆ET浓度,与正常人血浆ET含量作比较,以了解消化性溃疡患者血浆内皮素(ET)水平变化及其临床意义。 对象和方法 一、对象:消化性溃疡患者97例(男81,女16),平均年龄38.8±16.6岁。其中胃溃疡21例,十二指肠溃疡活动期38例,十二指肠溃疡愈合期18例,溃疡合并出血25例。以上病例均由内镜确诊。正常对照组46例(男31,女15),平均年龄39.7±13.1岁,查体健康人群,无溃疡病史,排除消化系统疾病及肝、心、脑、肾、肺疾患。
In this paper, patients with gastric ulcer and duodenal ulcer diagnosed by gastroscopy were selected as the experimental group, their plasma ET levels were measured and compared with normal plasma ET levels to understand the changes of plasma endothelin (ET) level in patients with peptic ulcer and its clinical significance. Objects and methods A, object: 97 patients with peptic ulcer (male 81, female 16), the average age of 38.8 ± 16.6 years. Among them, there were 21 cases of gastric ulcer, 38 cases of duodenal ulcer active stage, 18 cases of duodenal ulcer healing and 25 cases of ulcer combined hemorrhage. The above cases were confirmed by endoscopy. The control group of 46 cases (male 31, female 15), the average age of 39.7 ± 13.1 years old, physical examination of healthy people, no history of ulcer disease, excluding digestive diseases and liver, heart, brain, kidney and lung disease.