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冠脉成形术的成功与否，主要取决于预防急性或亚急性阻塞而又不会引起出血的抗栓疗法的疗效。血管成形术时的内皮剥蚀和粥样硬化斑破裂，使内皮下成分和富含脂质的粥样硬化斑核心部位易受凝血因子的影响，而形成血栓。传统抗血小板药阿司匹林目前虽已发现了一些新的抗血小板药
The success of coronary angioplasty depends primarily on the efficacy of antithrombotic therapy in preventing acute or subacute obstruction without causing bleeding. Endothelial erosion and rupture of the atherosclerotic plaque during angioplasty expose the subendothelial components and the lipid-rich atherosclerotic plaque core to clotting factors and cause thrombus formation. Although traditional antiplatelet drugs aspirin has found some new antiplatelet drugs