论文部分内容阅读
目的:探讨鼻腔及鼻咽非霍奇金淋巴瘤的治疗方法。方法:回顾性分析2006-01-2010-10期间在我院收治的资料完整并经病理确诊的原发鼻腔及鼻咽非霍奇金淋巴瘤病例20例。结果:全组3年总生存率和完全缓解率分别是78%、47%。单纯化疗组和化疗加放疗组3年总生存率分别是75%、82%。单纯化疗组和化疗加放疗组获得完全缓解率分别是37%、55%。首程治疗后达完全缓解患者的3年生存率89%,未达完全缓解率患者3年生存率70%。ⅠE期和ⅡE期3年总生存率分别是92%、57%。结论:鼻腔,鼻咽部非霍奇金淋巴瘤单纯化疗与化疗加放疗疗效无明显区别。ⅠE期3年生存率明显高于ⅡE期,早期诊断可以提高患者的3年生存率。
Objective: To explore the treatment of nasal and nasopharyngeal non-Hodgkin’s lymphoma. Methods: A retrospective analysis of 20 cases of primary nasal and nasopharyngeal non-Hodgkin’s lymphoma with complete and pathologically confirmed data in our hospital from January 2006 to October 2010 was retrospectively analyzed. Results: The overall 3-year overall survival and complete remission rates were 78% and 47%, respectively. The 3-year overall survival rates of the chemotherapy alone group and chemotherapy plus radiotherapy group were 75% and 82%, respectively. The complete remission rate was 37% in the chemotherapy group alone and 55% in the radiotherapy and chemotherapy group. After the first course of treatment, patients with complete remission of 3-year survival rate of 89%, less than complete remission rate of 3-year survival rate of 70%. The 3-year overall survival rates in stage IE and stage IIE were 92% and 57%, respectively. Conclusion: Nasal and nasopharyngeal non-Hodgkin’s lymphoma chemotherapy alone and chemotherapy plus radiotherapy effect no significant difference. The 3-year survival rate of stage ⅠE was significantly higher than that of stage ⅡE. Early diagnosis could improve the 3-year survival rate of patients.