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随着抗菌素临床应用增多及实验方法改进,对抗菌素作用于细菌的机理有了进一步了解。近年来通过实验研究及临床观察进一步了解有些抗菌素对宿主的各种防卫系统有直接的反作用,包括影响机体的体液免疫功能和细胞免疫功能,现将国外研究近况综述如下:各类抗菌素对免疫功能的影响及其机理氯霉素对体液免疫功能的影响 Ambrose 等应用经牛血浆白蛋白及白喉类毒素注射和免疫后
With the increase of clinical application of antibiotics and the improvement of experimental methods, the mechanism of action of antibiotics on bacteria has been further understood. In recent years, through experimental research and clinical observation, we further understand that some antibiotics have direct adverse effects on various host defense systems, including humoral and cellular immune functions. The current status of foreign research is summarized as follows: Various types of antibiotics have significant effects on immune function And its mechanism of chloramphenicol on humoral immune function Ambrose and other applications of bovine serum albumin and diphtheria toxoid injection and immunization