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目的探讨老年格林-巴利综合征(GBS)的临床特点及治疗。方法将41例老年GBS与206例非老年CBS进行临床对比分析。结果老年组发病率较低,男女之比明显高于非老年组,多于冬春季发病,非老年组多于夏秋季发病。老年组脊神经型、暴发型和再发型的构成比高于非老年组;末梢感觉障碍急性型的构成比低于非老年组;并发症的发生率、病死率高于非老年组;以上差异均有显著意义。老年组死亡的主要原因是呼吸肌麻痹合并肺部感染。结论老年格林-巴利综合征有其临床特点,采取合理的综合治疗,积极防治并发症,提高机体免疫力是降低病死率,提高治愈率的关键。
Objective To investigate the clinical features and treatment of geriatric Guillain-Barre Syndrome (GBS). Methods 41 cases of elderly GBS and 206 cases of non-elderly CBS clinical comparative analysis. Results The incidence of geriatric group was lower, the ratio of male to female was significantly higher than that of non-geriatric group, more than that in winter and spring, and more in non-geriatric group than in summer and autumn. The composition ratio of spinal nerve type, fulminant type and recurrent type in the elderly group was higher than that in the non-elderly group. The constituent ratio of the acute type of peripheral sensory disturbance was lower than that in the non-elderly group. The incidence of complications and the mortality were higher than those in the non-elderly group. Have significant meaning The main cause of death in the elderly group is respiratory muscle paralysis with pulmonary infection. Conclusion The elderly Guillain-Barre syndrome has its clinical features. To take reasonable comprehensive treatment, to actively prevent and treat complications and improve immunity is the key to reduce the mortality and increase the cure rate.