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雄烯二酮、胰岛素和促黄体激素(LH)是调节卵巢颗粒细胞产生甾体激素的重要因素,分泌过多及激素间平衡失调会影响卵细胞的成熟。为观察高浓度雄烯二酮、胰岛素和LH对人卵颗粒细胞产生雌、孕激素的调节及三者的相互作用进行此项研究。实验所用人卵巢颗粒细胞是从因输卵管病变接受体外受精的妇女卵泡穿刺获得。将所取颗粒细胞置于
Androstenedione, insulin and luteinizing hormone (LH) are important factors that regulate the production of steroid hormones in ovarian granulosa cells. Excessive secretion and steroid imbalance affect the maturation of oocytes. To investigate the high concentrations of androstenedione, insulin and LH on human egg granulosa cells produce estrogen and progesterone regulation and the three interactions of this study. Human ovarian granulosa cells were obtained from follicular puncture in women receiving in vitro fertilization due to tubal pathology. Place the granule cells in place