苦参碱对豚鼠离体气管的影响(摘要)

• 作 者: 查力 杨哲慧 曾庆卓 钟恒宁 黄能慧 夏炳南
• 机 构: 贵阳医学院药理学教研室,贵阳医学院药理学教研室,贵阳医学院药理学教研室,贵阳医学院药理学教研室,贵阳医学院药理学教研室,贵阳医学院药理学教研室 进修生,进修生
• 出 处: 贵阳医学院学报
• 发表日期: 1983年02期
• 关键词: 离体气管 苦参碱 恒温水浴槽 组胺 软骨部 量效曲线 气管 收缩作用 摘要 Krebs

为进一步探讨苦参对气管作用及其原理,从苦参总碱中分离经鉴定为苦参碱(Materine,M),试验了其对豚鼠离体气管作用及其与组胺的关系。取雌雄豚鼠离体气管剪成环状,把各环软骨部相互连结,剪开或剪去部分软骨,做成气管链标本,置于含 Krebs-Ringers 液的自置恒温水浴槽内(13ml),连续通入 O_2

In order to further investigate the effect of Sophora flavescens on trachea and its principle, it was identified as matrine (Materine) from the total alkaloids of Sophora flavescens. Its effect on isolated trachea of ​​guinea pigs and histamine were tested. The isolated trachea was cut into rings in female and male guinea pigs, and the cartilaginous parts were connected to each other. The cartilage was cut or cut to make tracheal chain specimens and placed in a self-contained constant-temperature water bath containing Krebs-Ringers (13 ml). , continuous access to O_2