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目的观察脑保护下颈动脉狭窄支架成形术的临床疗效和安全性。方法回顾性分析2003年4月至2010年6月1 328例脑保护下行支架成形术治疗颈动脉狭窄患者的临床资料,分析手术的安全性和有效性。结果 1 328例患者均顺利将脑保护装置于颈动脉入颅处,患者治疗前颈动脉的狭窄率为(88.2±6.7)%,治疗后为(19.2±11.1)%,治疗后颈动脉狭窄明显减轻(P<0.01)。其中768例患者进行了平均1年随访,无1例死亡、缺血性脑卒中发生。结论脑保护下行颈动脉狭窄支架成形术治疗颈动脉狭窄、预防缺血性脑卒中安全、有效。
Objective To observe the clinical efficacy and safety of brachial carotid stenosis under cerebral protection. Methods The clinical data of 13 328 patients with carotid artery stenosis undergoing cerebral protection for stenting from April 2003 to June 2010 were analyzed retrospectively to analyze the safety and effectiveness of the surgery. Results All 1 328 patients successfully penetrated the cerebral protection device into the skull of the carotid artery. The stenosis rate of the carotid artery was (88.2 ± 6.7)% before treatment and (19.2 ± 11.1)% after the treatment. The carotid artery stenosis was obvious after treatment Reduce (P <0.01). Of these 768 patients were followed up for an average of 1 year, none died and ischemic stroke occurred. Conclusion Cerebral protection of carotid stenosis and stent implantation in the treatment of carotid artery stenosis and prevention of ischemic stroke is safe and effective.