A negative feedback loop controls ROS production in plant immunity

• 作 者: Michael Wrzaczek
• 机 构: Institute of Plant Molecular Biology,Biology Centre,Czech Academy of Sciences,370 05 ?eské Budějovic
• 出 处: 分子植物（英文版）
• 发表日期: 2021年8期

Over the past two decades the view of reactive oxygen species(ROS)as merely cytotoxic compounds has changed considerably(Waszczak et al.,2018).While still being considered as reactive chemicals with potentially devastating detrimental effects,ROS have been shown to be used by plants and animals alike as messengers in numerous signaling networks,including responses to biotic and abiotic environmental cues as well as developmental processes(Waszczak et al.,2018;Zandalinas et al.,2020).The production of ROS as by-products of cellular metabolism as well as the active production of ROS in different subcellular localization is tightly controlled(Castro et al.,2021).However,mechanistic details on how ROS are sensed and how the specificity in ROS signaling is achieved remain scarce.Few intracellular ROS sensors have been characterized on a molecular level,and recently the first sensor for extracellular ROS,HPCA1,has been identified(Wu et al.,2020).However,the broad involvement of ROS in signal transduction in plants suggests the existence of a far larger and more diverse sensory array.