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目的:探讨男性无症状脑梗死(SBI)与腹型肥胖及血生化指标间的相关性。方法:选取开滦集团高管健康查体男性职工645例,采用病例对照研究方法,以腰围≥90 cm作为腹型肥胖诊断标准,将其分为腹型肥胖组474例和腰围正常组171例。依据头颅CT诊断为SBI170例,并测定血糖、血脂等血生化指标,收集临床资料。分析男性SBI与腹型肥胖者及血生化指标间的关系。结果:与非SBI组比较,SBI组年龄、高血压病史、糖尿病史、腹型肥胖例数、收缩压、腰围、血糖、低密度脂蛋白胆固醇均高于非SBI组;腹型肥胖组饮酒例数、高血压病史、SBI、体质量指数、血糖、甘油三酯高于腰围正常组(P<0.01,P<0.05),腹型肥胖组年龄、高密度脂蛋白胆固醇低于腰围正常组(P<0.01)。以SBI为因变量的多元逐步回归分析显示,依次筛选出腹型肥胖、收缩压(P<0.01,P<0.05)与其相关。结论:腹型肥胖、收缩压增高可能是SBI患者的独立危险因素。
Objective: To investigate the correlation between asymptomatic cerebral infarction (SBI) and abdominal obesity and blood biochemical markers in men. Methods: A total of 645 male health workers from Kailuan Group were enrolled in this study. A case-control study was conducted. The waist circumference ≥90 cm was used as diagnostic criteria for abdominal obesity, which was divided into 474 cases of abdominal obesity and 171 cases of normal waist circumference . According to the diagnosis of head CT, SBI170 cases, and determination of blood glucose, blood lipids and other biochemical indicators, to collect clinical data. Analysis of the relationship between male SBI and abdominal obesity and blood biochemical indicators. Results: SBI group had higher age, history of hypertension, history of diabetes, abdominal obesity, systolic blood pressure, waist circumference, blood glucose and low density lipoprotein cholesterol than non-SBI group, and alcohol consumption in abdominal obesity group SBP, body mass index, blood glucose, triglyceride were higher than those in the normal group (P <0.01, P <0.05). The age, HDL cholesterol of the abdominal obesity group were lower than those of the normal group (P <0.01). Multiple stepwise regression analysis with SBI as the dependent variable showed that abdominal obesity and systolic blood pressure (P <0.01, P <0.05) were screened in turn. Conclusion: Abdominal obesity and increased systolic blood pressure may be independent risk factors for patients with SBI.