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本文报道一例以脊髓长束变性(SCLTD)为特征的获得性免疫缺陷综合征(AIDS),以往尚未见报道。患者男性,36岁,同性恋者。于1982年3月患有卡氏肺囊虫病,播散性鸟型分支杆菌病、肛周单纯疱疹、鹅口疮、巨细胞包涵体病、结肠炎和视网膜炎。用过异烟肼、乙胺丁醇、链霉素、环丝氨酸、利福平、胸腺素等治疗无效。同年7月发生两下肢进行性瘫痪伴感觉异常、腿痛、肌萎缩。同年11月癫痫大发作一次。1983年1月发生截瘫和深感觉障碍。脑脊液单纯疱疹病毒(HSV)和巨细胞病毒(CMV)培养,ECHO病毒补体结合试验(CF)、Coxsackie B1-6 CF,弓形体间接荧光抗体(IFA)(IgG和IgM),CMV CF和真菌CF都阴性。血清E-B IFA滴度IgG
This article reports an example of acquired immunodeficiency syndrome (AIDS) characterized by long bundle degeneration (SCLTD) of spinal cord that has not been reported in the past. Male patient, 36 years old, gay. March 1982 suffering from Pneumocystis carinii, disseminated Mycobacterium avium, perianal herpes simplex, thrush, giant cell inclusion body disease, colitis and retinitis. Used isoniazid, ethambutol, streptomycin, cycloserine, rifampicin, thymosin and other treatment is invalid. In the same year in July occurred two lower limb paralysis with sensory abnormalities, leg pain, muscle atrophy. The same year in November epilepsy attack once. Paraplegia and deep sensory disturbances occurred in January 1983. Cerebrospinal herpes simplex virus (HSV) and cytomegalovirus (CMV) cultures, ECHO virus complement fixation assay (CF), Coxsackie B1-6 CF, Toxoplasma indirect fluorescent antibody (IFA) (IgG and IgM), CMV CF and fungal CF Are negative. Serum E-B IFA titer IgG