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目的研究可达龙(盐酸胺碘酮)早期静滴对急性前壁心肌梗死后心律失常发生率及对心律失常性死亡率的影响。方法回顾性对比研究自2004年1月-2006年2月收住我院急诊CCU病房急性前壁心肌梗死患者,治疗组:52例,对照组:54例。所有患者入院后均给予扩冠、抗凝、时间窗范围内溶栓等治疗,治疗组给予NS100ml+可达龙300mg静滴一次,半小时-1小时滴完。24h内监测血压、心率、心电监护、电解质及胸痛等情况。结果治疗组:24h内总心律失常发生者24例,占46.1%,因恶性心律失常死亡者4例,占7.6%;对照组:24h内总心律失常发生者34例,占62.9%,因恶性心律失常死亡者7例,占12.9%。结论急性前壁心肌梗死早期预防性静滴可达龙,24小时内总心律失常发生率明显下降,因心律失常导致的死亡率亦明显下降。
Objective To investigate the effect of early telmisartan (Amiodarone Hydrochloride) intravenous infusion on the incidence of arrhythmia after acute anterior myocardial infarction and its effect on arrhythmogenic mortality. Methods A retrospective comparative study of patients with acute anterior myocardial infarction received CCU ward in our hospital from January 2004 to February 2006. The treatment group: 52 cases and control group: 54 cases. After admission, all patients were given crown expansion, anticoagulation and thrombolytic therapy within the time window. The treatment group was treated with NS100ml + up to 300mg intravenously once a hour for 1 hour and half hour. 24h blood pressure monitoring, heart rate, ECG monitoring, electrolytes and chest pain and so on. Results In the treatment group, there were 24 cases (46.1%) of the total arrhythmia occurred in 24h and 4 died of malignant arrhythmia (7.6%). In the control group, 34 cases (62.9%) of the total arrhythmia occurred within 24 hours, Seven patients died of arrhythmia, accounting for 12.9%. Conclusions Early prophylaxis of anterior myocardial infarction in acute anterior myocardial infarction can reach the dragon. The incidence of total arrhythmia in 24 hours is significantly decreased, and the mortality rate due to arrhythmia is obviously decreased.