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一般认为,结肠癌是经过多过骤过程形成的,通常须数年才发生表型的细胞转化。在此过程中可能改变的一个表型特征是细胞的分化状态。迄今全世界已获得有数种异种抗血清和MAbs。它们可与许多抗原反应以及和结肠癌与正常结肠上皮起免疫反应。用这些抗体检测的抗原可根据其组织分布分成
It is generally believed that colon cancer is formed through a multi-step process that typically takes years to undergo phenotypic cell transformation. A phenotypic characteristic that may change during this process is the cellular differentiation status. To date, several different antisera and MAbs have been obtained worldwide. They are immunoreactive with many antigens as well as colon and normal colonic epithelia. The antigens detected with these antibodies can be divided according to their tissue distribution