对双胎孕中期羊膜腔穿刺注射亚甲蓝后胎儿死亡的研究

• 作 者: 李迺珺
• 出 处: 国外医学(计划生育分册)
• 发表日期: 1997年01期
• 关键词: 羊膜腔穿刺 胎孕 羊膜囊 产前诊断 肠闭锁 时用 对双 威尔 早期自然流产 接触组

孕中期双胎妊娠为遗传学目的进行羊膜腔穿刺,过去用注射亚甲蓝方法鉴别双胎不同的羊膜囊。最近连续两篇报道在孕中期羊膜腔穿刺时注射亚甲蓝与小肠闭锁有关。其它应用过的染料包括靛青、姻脂和刚果红,尚未报道造成有害的后果。在80年代澳大利亚的一些地区曾广泛使用亚甲蓝。经调查表明在新南威尔洲近1/3双胎在产前诊断时用过

In the second trimester of pregnancy, amniocentesis is carried out for genetic purposes. In the past, methylene blue was used to identify different amniotic sacs of the twins. Two consecutive reports of methylene blue in the second trimester during amniocentesis have been associated with small bowel atresia. Other applied dyes, including indigo, agar, and congo red, have not been reported to have deleterious consequences. Methylene blue has been widely used in some parts of Australia during the 1980s. Surveys show that nearly a third of all twins in New South Wales were used during prenatal diagnosis