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目的 评价鼻腔中谷胱甘肽含量及其对慢性鼻炎的治疗价值。方法 测定正常和病理状态下鼻腔中谷胱甘肽的含量 ,并用鼻腔滴注观察其对慢性鼻炎的疗效。结果 正常成人和鼻病理状态下谷胱甘肽的水平非常低 ,两者之间无显著差异 ;谷胱甘肽可显著改善患者的鼻开放感觉 ,减少鼻溢液。结论 谷胱甘肽的鼻腔应用可显著改善慢性鼻炎的临床症状 ,其作用可维持较长时间
Objective To evaluate glutathione content in nasal cavity and its therapeutic value on chronic rhinitis. Methods The contents of glutathione in the nasal cavity under normal and pathological conditions were measured. The effect of glutathione on the chronic rhinitis was observed by intranasal instillation. Results In normal adult and nasal pathological conditions, the level of glutathione was very low with no significant difference between the two. Glutathione could significantly improve nasal opening sensation and reduce nasal discharge. Conclusion Glutathione nasal application can significantly improve the clinical symptoms of chronic rhinitis, and its role can be maintained for a long time